The 6 Best Weight Loss Pills

Do you have a problem with your weight? You have been following all kinds of dieting trends, but do your weight loss goals still seem an unattainable dream? If your answer to the above 2 questions is an emphatic ‘Yes’, then a weight loss pill may be a good option for you.

You should know that a weight loss drug works effectively only with a well-balanced diet and exercise. If you are willing to put in the effort to avoid junk foods and sugar-laden treats, instead include a variety of fruits, vegetables and protein sources into your diet, then these pills will help speed up your weight loss.

Your total calorie intake should be lower than your calorie output, meaning you need to avoid heavy calorie meals and be physically active enough to burn off those extra pounds. These weight loss pills also promote fat burning and will help you reach your weight loss goals.

Weight loss drugs work in three main ways:

  • Thermogenesis is when ingredients in the weight loss drug increase the metabolic rate in the body converting fat into expended energy.
  • Enhances the feeling of satiety removing hunger pangs and reducing appetite
  • Drugs that block or slow down the absorption of fat from foods.

Check out these top 6 weight loss supplements that are available online.

Top 6 Weight Loss Supplements of 2020

#1 PhenQ

PhenQPhenQ has a blend of natural ingredients that have been proven scientifically to help in weight loss. The ingredients are of the highest quality and the supplement is manufactured in a GMP approved facility. The properties of capsicum, caffeine, piperine and niacin aid in reducing fat storage in the body.

The components work on the biopath of thermogenics that promotes body heat, thereby converting fat into energy. Indications of stopping more fat cells from forming have been attributed to the presence of piperine (black pepper). Caffeine also enhances the fat burning process. Nopal cactus is rich in fiber and provides the essential amino acids.

Each bottle of PhenQ has 60 pills. The recommended dosage is 2 pills per day. The facilities are in the UK and the USA and are FDA registered. The pill can be taken with breakfast and another with lunch. Since it contains caffeine it would be advisable to watch out for excess caffeine intake if you are a coffee drinker. Avoid this pill after 3 pm as it may interrupt your sleep duration. PhenQ can be continued even after achieving your health goals and it is 100% natural and vegan pill. A quick consultation with your physician will be useful.

The company provides a 60-day money-back guarantee. The user can return the pills with its original packing within 67 days of receiving it. A full refund will be extended without the applicable shipping charges.


  • All-natural ingredients
  • Can be consumed by vegetarians and vegans
  • Involves the process of thermogenesis
  • A 60-day money-back offer

#2 Phen24

Phen24 as the name suggests is a 24-hour working formulation. It has two phases or comes in two different bottles that have different ingredients. The formulation works on day and night time metabolism of the body. The highest quality ingredients are used in these pills.

Each bottle contains 30 capsules. The day capsule should be taken with breakfast and the night pill (2 pills) should be taken 15 minutes before the evening meal with 1 or 2 glasses of water. The night dosage contains no stimulant and therefore will not interrupt the sleep pattern.

The day pills contain zinc, manganese, copper, iodine, caffeine, guarana extract, L-phenylalanine, and cayenne powder. The night pills contain ascorbic acid, calcium D-pantothenate, pyridoxine HCl, chromium, thiamine Hcl, D-biotin, molybdenum, glucomannan, green tea extract, and hops extract. The pills work on the stored fat using the thermogenic process.

Both the day and night pills are 100% vegetarian and vegan-friendly. A purchase of 2 boxes of these pills will come along with a third box that is given free. A 60-day money-back offer can be availed for 67 days from the time when it was delivered to the customer. Shipping charges paid by the customer are excluded in this case.

These pills are not intended for children and should not be consumed by pregnant or nursing women, diabetics, those with depression, endocrine or autoimmune disorders, prostate cancer or hypertrophy, liver or kidney disease, breast or testicular cancer.


  • Works on the day and night metabolism of the body
  • No stimulant present in the night capsules
  • Vegan- friendly
  • Free Shipping

#3 alli Orlistat

Alli OrlistatAlli Orlistat is the only over-the-counter weight loss pill that has been approved by the FDA. It means that a prescription is not required to use this pill. As claimed by the company that manufactures this product, GSK Consumer Healthcare, the pill has been subjected to over 100 clinical studies.

Each container has 120 capsules. The serving size is 3 capsules a day that can be taken with meals. The active ingredient is orlistat that attaches itself to certain enzymes to break down fat. This product is for people who are overweight. A trial pack is first sent to the customer with a ‘Read Me’ brochure that explains everything you need to know about using the product. The effects of the pills would cause the user to visit the bathroom quite often as at least 25% fat that is not absorbed gets eliminated. It is advised that meals should contain no more than 15 grams of fat.

The other ingredients used are FD&C Blue No.2 (indigotine, which is a colorant and an inactive ingredient), gelatin, iron oxide, microcrystalline cellulose, povidone, sodium lauryl sulfate, sodium starch glycolate, talc, and titanium dioxide.

The company offers a 45-day money-back guarantee if the user is not completely satisfied with the product. The capsule does not contain any stimulants. It is small in size and easy to swallow.


  • The only FDA approved over-the-counter weight loss pill
  • Does not contain any stimulants
  • Easy to swallow pills
  • 45-day money-back guarantee

#4 Hydroxycut Hardcore Elite

Hydroxycut Hardcore EliteHydroxycut Hardcore Elite claims to be a super thermogenic capsule backed by scientific evidence. The key ingredient in this product is C. Canephora Robusta. It also contains forskohlii, theobromine, yohimbine, and L theanine.  All ingredients used are disclosed and tested by a third-party agency for purity, quality, and consistency.

For intake tolerance, only one capsule should be taken on the first day. On day 2 and 2 the user can take 2 capsules. From day 4 the consumer can take 2 capsules twice daily. These pills should be taken 30 to 60 minutes before the two largest meals of a day, which are breakfast and lunch.  At no point in time should be dosage exceed 4 capsules a day in a 24-hour period. Each bottle has 100 rapid release thermogenic capsules.

The best outcome is after a 60-day period of use of these capsules accompanied by a proper diet and exercise. The use of this supplement should not go beyond 8 weeks.  It should not be consumed for at least 5 hours before bedtime. The user should drink at least 10 glasses of water each day when using this thermogenic supplement. Each serving (2 capsules) contains 270 mg of caffeine.

The gelatin capsule is made up of FD &C Blue No.1, FD & C Red No.40 and titanium dioxide. The other ingredients are magnesium stearate silicon dioxide and microcrystalline cellulose.


  • Rapid release capsules
  • With key ingredient  C. Canephora Robusta
  • Contains yohimbine, and L theanine.
  • Third-party tested

#5 Animal Cuts

Animal Cuts comes with multiple supplements that serve various health benefits. It has 42 packs with 9 pills per packet. The capsules have to be taken on an empty stomach with one pack in the morning and the other 4 to 6 hours later. The cycle period is for 3 weeks. It should be followed by a one-week off-cycle. This schedule can be followed until the weight loss goal has been achieved.  A light diet is ideal when taking this product.

The capsules have colors that indicate the health advantage it delivers. If you are a coffee drinker you may want to avoid the caffeine stimulant capsule. It is advisable to consult a doctor before using this supplement. This supplement is not gender-specific. The product is not intended for children and should not be consumed by breastfeeding and pregnant women. Those with a medical condition or on other medications should avoid using this weight loss supplement.

All quality checks from the start to the finish of the manufacturing process are followed. The claims made by the company on the label are delivered by the product. The supplement is made in the USA. The facility adheres to the norms of GMP. Other supplements of Animal Cut can be stacked along for enhanced results. A consultation with a doctor is mandatory for the use of this product.


  • Multiple supplements that deliver various benefits
  • Product is not gender-specific
  • Stringent quality checks followed
  • Company has a 30-year reputation for supplement production

#6 Quadralean Thermo

Quadralean ThermoQuadralean Thermo is backed by scientific evidence. It contains caffeine, extracts from bitter orange, choline, and alpha-GPC. Grains of paradise and cayenne pepper fruit extract jump-starts the thermogenic process of this supplement. This product can be used as a pre-workout supplement and at other times too.

The product is manufactured in a GMP certified facility. All ingredients are disclosed and tested for the quality and integrity of its ingredients. The bottle contains 180 capsules with a serving size of 3 capsules a day. In each serving the product delivers 500mg of CLA (conjugated linoleic acid) along with 300 mg of choline bitartrate and 50 mg of alpha GPC, 25mg of grains of paradise, and 500 mg of L Carnitine. 200 mg of natural caffeine also gets delivered in each serving.

The other ingredients that are present in this supplement are gelatin, silicon dioxide, magnesium stearate, titanium dioxide, and plant cellulose. This supplement should not be used by those under the age of 18, lactating and pregnant women. A doctor’s consultation is important for those who are on other medications or have a medical condition.


  • Supplement is backed by scientific evidence
  • Causes no jitters or crashes
  • Can be used as a pre-workout supplement and at other times
  • Contains grains of paradise

Who Is The Right Candidate For Weight-Loss Pills?

Anyone can use an over-the counter weight loss pill as these usually contain natural ingredients such as caffeine, green tea, Garcinia cambogia extract, etc. which are generally safe for consumption. These fat burners will help boost the effort of anyone who wants to lose some extra body fat.

Children, teenagers, pregnant women or breastfeeding moms should avoid such supplements. It’s best to consult a doctor if you are overweight and suffering from chronic health issues such as diabetes, cholesterol or high blood pressure.

The following criteria will be considered by your doctor if you have not been able to lose weight following a diet change and regular exercise.

  • Your body mass index exceeds 30
  • A preexisting medical problem of diabetes and high blood pressure with obesity and your MMI (Muscle Mass Index) is more than 27

A review of your health history will be taken up by your doctor along with the possibility of interaction with your present medication.

Sustained lifestyle changes are vital for weight loss pills to be effective. An additional 3 to 7 percent of weight loss can be achieved over a period of 12 months of regular exercise and proper diet. Long term regulation with 5 to 10 percent weight loss can result in lower blood pressure and triglyceride with a healthy blood sugar level.

How Long Does the Effect of Weight Loss Pills Last?

It depends on whether the drug is having a positive influence on weight loss and that there are no adverse side effects. In this case, your doctor may not specify a time frame for the medication.

If for 12 weeks you have not lost at least 5 percent of your total body weight your doctor would probably change the medication or treatment plan. A healthy lifestyle change may not cause weight gain once these drugs are stopped.

A review study of 28 long-term trials in 2016 came to the conclusion that lifestyle changes and a prescribed weight loss drug increase the chances of attaining ‘clinically meaningful’ loss of weight in a year’s time. The term ‘clinically meaningful’ indicates that the person has lost sufficient weight wherein the risk of heart disease, diabetes, and other chronic maladies are reduced.

5 Effective Ingredients in Weight Loss Supplements

Whether pills, supplements or specialized diets are used for weight loss, certain natural ingredients and food sources are found to be common among them.

Let’s take a look at some of the most effective ingredients that benefit weight loss.

1. Caffeine

Caffeine is a stimulant that enhances energy through thermogenics (heat-producing) and reduces the hunger feeling for a short duration. It seems to increase in expending energy even in a non-active state.

A study that was published in the ‘Obesity A Research Journal’ detailed the effects of a green tea-caffeine mixture on weight management in subjects who were habitual to caffeine intake and moderately obese. The 76 participants were of the same gender, age, BMI, height, and body mass. They were given a low energy diet for four weeks followed by 3 months of weight maintenance during which period they were given a green tea caffeine mixture every day.

It resulted in a weight reduction of approximately 6 kgs. A feeling of being full was evident among the participants.

Summary: Caffeine intake reduced weight by boosting metabolism and fat oxidation.

2. Garcinia Cambogia

Garcinia Cambogia is a tamarind that grows in southwest India, Myanmar, and Indonesia. It is used in Indian cuisine and has carved for itself a sizable share in the weight loss industry.

Garcinia cambogia is a fruit that contains hydroxycitric acid, which is thought to help weight loss. Scientific studies on the extracts from this fruit have been noted for its weight loss properties. The chemical hydroxycitric acid (HCA) was first studied in the 1960s.

A calcium-potassium salt of HCA was studied in an investigation that involved 90 obese volunteers who had a BMI (Body Mass Index) of 3050kg/m2.

The subjects were divided into three groups. Group A was given a daily dose of 2,800 mg of HCA. Group B was given a blend of HCA (4,667 mg) and niacin-bound chromium (4mg) and Gymnema Sylvestre extract (GSE). Group C was given a placebo.

All of them consumed 2,000 kcal diet per day and were involved in a walking session for 30 minutes daily. 82 participants completed the study. After an 8 week period, it was observed that body weight and BMI reduced by 5.5% in group A. Fat metabolites exit through urination increased by 32 to 109%.

Serotonin increased by 44.5%. Serotonin performs many functions in the body. It is known to influence mood, appetite, digestion, and sleep. Group B that was given a combination of supplements showed higher results in the above parameters. It was also noted that there were no adverse side effects.

Summary: The study concluded that Garcinia Cambogia is highly effective in weight loss management. Garcinia Cambogia is available as a pill.

3. Green Tea Catechins

Extracts from green tea are called catechins. Catechins are natural antioxidants that prevent cell damage. The Journal of Nutrition has noted a study that was conducted to determine the effect of green tea catechin on body weight.

132 subjects who were overweight were given a beverage with 625 mg catechins with 39mg caffeine or a control drink of only 39mg caffeine for a period of 12 weeks. The volunteers maintained a constant energy intake and undertook approximately 180 minutes of moderate to intense exercise every week.

Measurement of body composition, abdominal fat regions and clinical laboratory tests were taken before the test period and in the twelfth week. The experiment demonstrated a significant loss of body weight among participants of the catechin group. Changes in fasting serum triglycerides, abdominal fat and subcutaneous abdominal fat (fat that is evidently noticeable lying just below the skin) were observed.

Summary: Green tea catechins promote fat loss in the abdomen and also positively affect serum triglycerides. Many diet pills contain green tea because this may increase the body’s ability to burn fat, and especially fat in the stomach area.

4. CLA (Conjugated Linoleic Acid)

Conjugated linoleic acid is a type of fatty acid that is mainly found in meat and dairy products.  Found naturally in grass-eating animals like cows, CLA studies commenced in the 1980s. Some of the properties of CLA that were investigated were its anti-inflammatory, anticarcinogenic and anti-obesity properties.  It became more popular when research demonstrated its effect on weight management.

A study conducted in the early 2000s was published in the Journal of Nutrition. The trial was for a period of two years where obese subjects were given 3.4 grams of CLA to be ingested every day. The experiment recorded a consistent decrease in body fat mass. The initial 6 months fat reduction was the highest. CLA worked on increasing the rate of metabolism in the body. Those with higher fat body mass were the most benefited.

Summary: Studies have recorded that CLA supplementation increased the rate of metabolism and promoted fat burning.

5. Glucomannan

Glucomannan is found in the root of the elephant yam (konjac). It is fibrous and absorbs water, giving a feeling of satiety. It is known to positively affect blood sugar, cholesterol, and triglycerides in the blood. It feeds the good bacteria in the stomach. Glucomannan is an effective treatment for constipation.

A 2005 study proved that glucomannan was effective in reducing the weight of healthy obese subjects. The study compared glucomannan to the fiber supplements of guar gum and alginate. 176 overweight men and women were given either the active fiber supplement or a placebo. The trial was for a period of 5 weeks. They also consumed a diet of 1200kcal per day.

At the end of the 5-week experiment, it was found that glucomannan brought about body weight reduction and the addition of guar gum and alginate did not seem to add to the effect.

Summary: Glucomannan plays a key role in weight reduction and can be considered as the main ingredient in weight loss supplements.

The Bottom Line

Weight loss pills are not magic pills and cannot accomplish any weight loss goals on their own. Physical activity and a well-balanced diet should accompany any weight management program.

If you are already on medication or pregnant or breast-feeding ensure that you speak to your doctor before using any weight loss drug or supplement.

The above-mentioned weight loss pills are ranked among the best weight loss pills online by our research team. So compare them and see what suits your needs the best.